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Acetylcholine Receptor (AChR) Antibodies are autoantibodies that target acetylcholine receptors at the neuromuscular junction, impairing communication between nerves and muscles. Testing for these antibodies is primarily used to help diagnose myasthenia gravis, an autoimmune disorder characterized by muscle weakness and fatigue. The presence of AchR antibodies can confirm the diagnosis and assist in evaluating the severity of the condition, guiding treatment options.