Testosterone – Free Test: A laboratory test that measures the amount of free (unbound) testosterone in the bloodstream, which is the biologically active form of the hormone and plays a crucial role in various bodily functions.
Purpose: This test is primarily used to evaluate testosterone levels in individuals experiencing symptoms of testosterone deficiency or excess, such as low libido, fatigue, mood changes, infertility, or signs of androgen excess.
Test Methodology: A blood sample is taken, and the concentration of free testosterone is typically measured using methods such as equilibrium dialysis or advanced immunoassays. Total testosterone levels may also be assessed for a comprehensive evaluation.
Normal Range: Free testosterone levels can vary based on factors such as age, sex, and laboratory reference ranges. In adult males, normal values are generally between 5 to 21 ng/dL, while for females, the normal range is much lower.
Interpretation:
Low Levels: May indicate testosterone deficiency, which can result from conditions such as hypogonadism, pituitary disorders, or certain chronic illnesses.
High Levels: May suggest conditions like androgen-secreting tumors, polycystic ovary syndrome (PCOS) in women, or other hormonal imbalances.
Clinical Relevance: Measuring free testosterone is essential for diagnosing hormonal imbalances and conditions related to testosterone metabolism, helping guide treatment options such as hormone replacement therapy or further diagnostic testing.
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